Read BookLipoprotein Metabolism and Atherogenesis

[Download PDF.pJAX] Lipoprotein Metabolism and Atherogenesis

[Download PDF.pJAX] Lipoprotein Metabolism and Atherogenesis

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Book Details :
Published on: 2012-12-06
Released on: 2012-12-06
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Atherosclerosis leading to coronary heart disease and to cerebrovascular disorders is the number one cause of death in industrialized societies. For the last two decades, great ad­ vances have been made in understanding the pathogenesis of those disorders. Recent studies have revealed that the earliest event in atherogenesis is the adhesion of circulating leukocytes to the vascular endothelial cells and their migration into the subendothelial space. These cells are known to playa central role in the formation of a fatty streak consist­ ing of lipid-laden foam cells. As pathological events continue, the lesion is converted to a more fibrous lesion associated with vascular smooth muscle cells. To solve the enigma of this complicated process, intensive studies in molecular biology have disclosed the genes involved in those events. Some of the genes have been verified by creation of novel animal models, which have led to novel therapeutic strategies for subjects with atherosclerosis. This volume contains papers presented at the International Symposium on Lipoprotein Metabolism and Atherogenesis held in Kyoto December 5-8, 1998, supported in part by the Japan Intractable Diseases Research Foundation. The following three topics were the focus of the three-day program: I) The molecular approach to studying risk factors and prevention 2) The creation of novel animal models 3) Lipoprotein disorder as a cause of activation of vascular endothelial cells Thirty distinguished researchers from the United States, the United Kingdom, Austria, Finland, Australia, and Japan were invited. OMIM Entry - + 107730 - APOLIPOPROTEIN B; APOB Apolipoprotein B is the main apolipoprotein on chylomicrons and low density lipoproteins (LDLs). It occurs in the plasma in 2 main forms apoB48 and apoB100. The ... Cholesterol Efflux Capacity High-Density Lipoprotein ... Original Article. Cholesterol Efflux Capacity High-Density Lipoprotein Function and Atherosclerosis. Amit V. Khera M.D. Marina Cuchel M.D. Ph.D. Margarita de ... LRP1 - Wikipedia Low density lipoprotein receptor-related protein 1 (LRP1) also known as alpha-2-macroglobulin receptor (A2MR) apolipoprotein E receptor (APOER) or cluster of ... Lipoproteina - Wikipedia Una lipoproteina un composto organico formato da una proteina coniugata con una componente lipidica. I lipidi possono essere legati alle proteine mediante legame ... VLDL cholesterol: Is it harmful? - Mayo Clinic What is VLDL cholesterol? Can it be harmful? Answers from Francisco Lopez-Jimenez M.D. Very-low-density lipoprotein (VLDL) cholesterol is produced in the liver and ... Atherosclerosis - Wikipedia Atherosclerosis (also known as arteriosclerotic vascular disease or ASVD) is a specific form of arteriosclerosis in which an artery-wall thickens as a result of ... Intestinal Microbial Metabolism of Phosphatidylcholine and ... Background Recent studies in animals have shown a mechanistic link between intestinal microbial metabolism of the choline moiety in dietary phosphatidylcholine ... Lipoproteins Lipoprotein Metabolism and Disease [LDL HDL ... The lipoproteins page provides a detailed description of the structure and function of the lipoprotein particles found in the circulation as well as therapeutic means ... Advanced Search Circulation Type a term to search within all articles in this journal: e.g. stem cell Lipoprotein(a) - Wikipedia Lipoprotein(a) (also called Lp(a) or LPA) is a lipoprotein subclass. Genetic studies and numerous epidemiologic studies have identified Lp(a) as a risk factor for ...
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